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ENZYME entry: EC 2.3.1.237

Accepted Name
Neocarzinostatin naphthoate synthase.
Alternative Name(s)
Naphthoic acid synthase.
Reaction catalysed
Acetyl-CoA + 5 malonyl-CoA + 2 NADPH <=> 2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO(2) + 3 H(2)O + 2 NADP(+)
Comment(s)
A multi-domain polyketide synthase involved in the synthesis of neocarzinostatin in the bacterium Streptomyces carzinostaticus.
Cross-references
BRENDA2.3.1.237
EC2PDB2.3.1.237
ExplorEnz2.3.1.237
PRIAM enzyme-specific profiles2.3.1.237
KEGG Ligand Database for Enzyme Nomenclature2.3.1.237
IUBMB Enzyme Nomenclature2.3.1.237
IntEnz2.3.1.237
MEDLINEFind literature relating to 2.3.1.237
MetaCyc2.3.1.237
UniProtKB/Swiss-Prot
Q84HC6, NCSB_STRCZ

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