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ENZYME

ENZYME entry: EC 2.3.1.237

Accepted Name
neocarzinostatin naphthoate synthase
Alternative Name(s)
naphthoic acid synthase
Reaction catalysed
acetyl-CoA + 6 H(+) + 5 malonyl-CoA + 2 NADPH <=> 2-hydroxy-5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 3 H2O + 2 NADP(+)
Comment(s)
A multi-domain polyketide synthase involved in the synthesis of neocarzinostatin in the bacterium Streptomyces carzinostaticus.
Cross-references
BRENDA2.3.1.237
EC2PDB2.3.1.237
ExplorEnz2.3.1.237
PRIAM enzyme-specific profiles2.3.1.237
KEGG Ligand Database for Enzyme Nomenclature2.3.1.237
IUBMB Enzyme Nomenclature2.3.1.237
IntEnz2.3.1.237
MEDLINEFind literature relating to 2.3.1.237
MetaCyc2.3.1.237
Rhea expert-curated reactions2.3.1.237
UniProtKB/Swiss-Prot
Q84HC6, NCSB_STRCZ

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