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ENZYME entry: EC 2.3.1.245

Accepted Name
3-hydroxy-5-phosphooxypentane-2,4-dione thiolase.
Alternative Name(s)
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
Reaction catalysed
acetyl-CoA + dihydroxyacetone phosphate <=> 3-hydroxy-2,4-dioxopentyl phosphate + CoA
Comment(s)
The enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.
Cross-references
BRENDA2.3.1.245
EC2PDB2.3.1.245
ExplorEnz2.3.1.245
PRIAM enzyme-specific profiles2.3.1.245
KEGG Ligand Database for Enzyme Nomenclature2.3.1.245
IUBMB Enzyme Nomenclature2.3.1.245
IntEnz2.3.1.245
MEDLINEFind literature relating to 2.3.1.245
MetaCyc2.3.1.245
Rhea expert-curated reactions2.3.1.245
UniProtKB/Swiss-Prot
A7ZLX4, LSRF_ECO24;  Q8XAZ1, LSRF_ECO57;  B1XEA5, LSRF_ECODH;  
A8A070, LSRF_ECOHS;  B1IRU3, LSRF_ECOLC;  P76143, LSRF_ECOLI;  
B1LF98, LSRF_ECOSM;  A4WER0, LSRF_ENT38;  A6TEB4, LSRF_KLEP7;  
Q7N2D6, LSRF_PHOLL;  Q57HD9, LSRF_SALCH;  Q5PJE3, LSRF_SALPA;  
A9MZG5, LSRF_SALPB;  Q8Z2X9, LSRF_SALTI;  Q8ZKQ0, LSRF_SALTY;  
Q0T4L4, LSRF_SHIF8;  Q83L15, LSRF_SHIFL;  A1JJ51, LSRF_YERE8;  
A7FMK1, LSRF_YERP3;  Q1C134, LSRF_YERPA;  B2K3F7, LSRF_YERPB;  
Q7CG47, LSRF_YERPE;  A9R0S6, LSRF_YERPG;  Q1CN19, LSRF_YERPN;  
A4TQL9, LSRF_YERPP;  Q66EZ3, LSRF_YERPS;  B1JLQ4, LSRF_YERPY;  

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