ID 2.3.1.246 DE 3,5-dihydroxyphenylacetyl-CoA synthase. CA 4 H(+) + 4 malonyl-CoA = (3,5-dihydroxyphenyl)acetyl-CoA + 4 CO2 + 3 CoA CA + H2O. CC -!- The enzyme, characterized from the bacterium Amycolatopsis CC mediterranei, is involved in biosynthesis of the nonproteinogenic CC amino acid (S)-3,5-dihydroxyphenylglycine, a component of the CC vancomycin-type antibiotic balhimycin. DR Q939X3, DPGA_AMYBA ; G4V4T4, DPGA_AMYOR ; Q8KLK5, DPGA_STRTO ; //