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ENZYME

ENZYME entry: EC 2.3.1.247

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.247
Accepted Name
(5S)-5-amino-3-oxohexanoate:acetyl-CoA ethylamine transferase
Alternative Name(s)
3-keto-5-aminohexanoate cleavage enzyme
Reaction catalysed
(5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate
Comment(s)
  • Requires Zn(2+).
  • The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, belongs to a class of enzymes known as beta-keto acid cleavage enzymes (BKACE).
  • It is involved in the anaerobic fermentation of lysine. cf. EC 2.3.1.317, EC 2.3.1.318, and EC 2.3.1.319.
Cross-references
BRENDA2.3.1.247
EC2PDB2.3.1.247
ExplorEnz2.3.1.247
KEGG Ligand Database for Enzyme Nomenclature2.3.1.247
IUBMB Enzyme Nomenclature2.3.1.247
MEDLINEFind literature relating to 2.3.1.247
MetaCyc2.3.1.247
Rhea expert-curated reactions2.3.1.247
UniProtKB/Swiss-Prot
E3PRK0, KCE_ACESDB0VHH0, KCE_CLOAIQ8RHX2, KCE_FUSNN

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-