ENZYME entry: EC 2.3.1.250
Accepted Name |
[Wnt protein] O-palmitoleoyl transferase.
|
Alternative Name(s) |
Porcupine. |
Reaction catalysed |
(9Z)-hexadec-9-enoyl-CoA + [Wnt]-L-serine <=> CoA + [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine |
Comment(s) |
- The enzyme, found in animals, modifies a specific serine residue in
Wnt proteins, e.g. Ser(209) in human Wnt3a and Ser(224) in chicken
WNT1.
- The enzyme can accept C(13) to C(16) fatty acids in vitro, but only
(9Z)-hexadecenoate modification is observed in vivo.
- cf. EC 3.1.1.98.
|
Cross-references |
BRENDA | 2.3.1.250 |
EC2PDB | 2.3.1.250 |
ExplorEnz | 2.3.1.250 |
PRIAM enzyme-specific profiles | 2.3.1.250 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.250 |
IUBMB Enzyme Nomenclature | 2.3.1.250 |
IntEnz | 2.3.1.250 |
MEDLINE | Find literature relating to 2.3.1.250 |
MetaCyc | 2.3.1.250 |
UniProtKB/Swiss-Prot |
|
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