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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.3.1.263

Accepted Name
2-amino-4-oxopentanoate thiolase.
Alternative Name(s)
2-amino-4-ketopentanoate thiolase.
AKP thiolase.
Reaction catalysed
Acetyl-CoA + D-alanine <=> CoA + (2R)-2-amino-4-oxopentanoate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • The enzyme, characterized from the bacterium Clostridium sticklandii, is part of a degradation pathway of ornithine.
  • It is specific for acetyl-CoA and D-alanine.
Cross-references
BRENDA2.3.1.263
EC2PDB2.3.1.263
ExplorEnz2.3.1.263
PRIAM enzyme-specific profiles2.3.1.263
KEGG Ligand Database for Enzyme Nomenclature2.3.1.263
IUBMB Enzyme Nomenclature2.3.1.263
IntEnz2.3.1.263
MEDLINEFind literature relating to 2.3.1.263
MetaCyc2.3.1.263
UniProtKB/Swiss-Prot
E3PY98, ORTA_ACESD;  C1FW06, ORTA_UNKP;  E3PY97, ORTB_ACESD;  
C1FW07, ORTB_UNKP;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-