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ENZYME entry: EC 2.3.1.284

Accepted Name
3'-(hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase.
Reaction catalysed
3 3'-(hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-alpha,alpha-trehalose <=> 3,6,6'-tris-(hydroxy)phthioceranyl-2-palmitoyl(stearoyl)-2'-sulfo-alpha-alpha-trehalose + 2 2'-palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose
Comment(s)
  • The enzyme, present in mycobacteria, catalyzes the ultimate step in the biosynthesis of mycobacterial sulfolipids.
  • It catalyzes two successive transfers of a (hydroxy)phthioceranyl group from two diacylated intermediates to third diacylated intermediate, generating the tetraacylated sulfolipid.
Cross-references
BRENDA2.3.1.284
EC2PDB2.3.1.284
ExplorEnz2.3.1.284
PRIAM enzyme-specific profiles2.3.1.284
KEGG Ligand Database for Enzyme Nomenclature2.3.1.284
IUBMB Enzyme Nomenclature2.3.1.284
IntEnz2.3.1.284
MEDLINEFind literature relating to 2.3.1.284
MetaCyc2.3.1.284
UniProtKB/Swiss-Prot
O07801, CHP1_MYCTU

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