ID   2.3.1.286
DE   protein acetyllysine N-acetyltransferase.
AN   NAD(+)-dependent protein deacetylase.
AN   protein lysine deacetylase.
CA   H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose
CA   + L-lysyl-[protein] + nicotinamide.
CC   -!- The enzyme, found in all domains of life, is involved in gene
CC       regulation by deacetylating proteins.
CC   -!- Some of the 2''-O-acetyl-ADP-D-ribose converts non-enzymically to
CC       3''-O-acetyl-ADP-D-ribose.
DR   Q5AQ47, HST1_CANAL ;  C8V3W5, HST1_EMENI ;  P53685, HST1_YEAST ;
DR   Q5AW69, HST21_EMENI;  P0CS88, HST22_EMENI;  Q5A985, HST2_CANAL ;
DR   Q9USN7, HST2_SCHPO ;  P53686, HST2_YEAST ;  Q5A1W9, HST3_CANAL ;
DR   P53687, HST3_YEAST ;  Q5BE04, HST4_EMENI ;  Q9UR39, HST4_SCHPO ;
DR   P53688, HST4_YEAST ;  A0R2N3, NDP_MYCS2  ;  O28597, NPD1_ARCFU ;
DR   Q89LY4, NPD1_BRADU ;  Q8R9N6, NPD1_CALS4 ;  Q8FUC8, NPD1_COREF ;
DR   Q5L014, NPD1_GEOKA ;  A0QDH4, NPD1_MYCA1 ;  Q9I4L0, NPD1_PSEAE ;
DR   Q88A13, NPD1_PSESM ;  Q8ZU41, NPD1_PYRAE ;  Q9RL35, NPD1_STRCO ;
DR   O30124, NPD2_ARCFU ;  Q89EA6, NPD2_BRADU ;  Q8R984, NPD2_CALS4 ;
DR   Q8FRV5, NPD2_COREF ;  Q5KZE8, NPD2_GEOKA ;  A0QC96, NPD2_MYCA1 ;
DR   Q9I4E1, NPD2_PSEAE ;  Q885X7, NPD2_PSESM ;  Q8ZT00, NPD2_PYRAE ;
DR   Q8CJM9, NPD2_STRCO ;  Q882K4, NPD3_PSESM ;  Q87W79, NPD4_PSESM ;
DR   Q9YB13, NPD_AERPE  ;  Q9ZAB8, NPD_AGGAC  ;  O67919, NPD_AQUAE  ;
DR   Q81NT6, NPD_BACAN  ;  Q735N7, NPD_BACC1  ;  Q81BT4, NPD_BACCR  ;
DR   Q639M6, NPD_BACCZ  ;  Q6HH09, NPD_BACHK  ;  O07595, NPD_BACSU  ;
DR   Q8A3H9, NPD_BACTN  ;  Q6MJJ2, NPD_BDEBA  ;  Q7WLE5, NPD_BORBR  ;
DR   Q7VX46, NPD_BORPE  ;  A8MBU4, NPD_CALMQ  ;  Q9JN05, NPD_CAMJE  ;
DR   Q5HU51, NPD_CAMJR  ;  Q9A2S6, NPD_CAUVC  ;  Q7P1B9, NPD_CHRVO  ;
DR   Q97MB4, NPD_CLOAB  ;  Q8XNS6, NPD_CLOPE  ;  Q899G3, NPD_CLOTE  ;
DR   Q8NSM4, NPD_CORGL  ;  Q6A5T5, NPD_CUTAK  ;  Q9RYD4, NPD_DEIRA  ;
DR   A9A0B2, NPD_DESOH  ;  Q8X8E0, NPD_ECO57  ;  Q8FIM4, NPD_ECOL6  ;
DR   P75960, NPD_ECOLI  ;  Q839C6, NPD_ENTFA  ;  Q8REC3, NPD_FUSNN  ;
DR   Q9KEE5, NPD_HALH5  ;  Q5V4Q5, NPD_HALMA  ;  Q7VIN2, NPD_HELHP  ;
DR   Q9ZJW8, NPD_HELPJ  ;  O25849, NPD_HELPY  ;  Q88ZA0, NPD_LACPL  ;
DR   C1DBX3, NPD_LARHH  ;  Q72RR0, NPD_LEPIC  ;  Q8F3Z6, NPD_LEPIN  ;
DR   Q927A7, NPD_LISIN  ;  Q71W25, NPD_LISMF  ;  Q8Y3U2, NPD_LISMO  ;
DR   Q607X6, NPD_METCA  ;  Q8TWG0, NPD_METKA  ;  P66814, NPD_MYCBO  ;
DR   Q9CBW6, NPD_MYCLE  ;  Q73WM7, NPD_MYCPA  ;  A5U1J9, NPD_MYCTA  ;
DR   P9WGG2, NPD_MYCTO  ;  P9WGG3, NPD_MYCTU  ;  Q8ELR0, NPD_OCEIH  ;
DR   Q9CM50, NPD_PASMU  ;  B4EVF5, NPD_PROMH  ;  Q88BY5, NPD_PSEPK  ;
DR   Q9UZE7, NPD_PYRAB  ;  Q8U1Q1, NPD_PYRFU  ;  O58669, NPD_PYRHO  ;
DR   Q8Y015, NPD_RALN1  ;  Q7UFQ9, NPD_RHOBA  ;  Q6N6U0, NPD_RHOPA  ;
DR   Q97VX5, NPD_SACS2  ;  P0A2F3, NPD_SALTI  ;  P0A2F2, NPD_SALTY  ;
DR   Q8EFN2, NPD_SHEON  ;  Q83RR8, NPD_SHIFL  ;  Q5WKC8, NPD_SHOC1  ;
DR   Q53700, NPD_STAA8  ;  Q5HE07, NPD_STAAC  ;  P66815, NPD_STAAM  ;
DR   P66816, NPD_STAAN  ;  Q6GEN2, NPD_STAAR  ;  Q6G7B7, NPD_STAAS  ;
DR   Q8NVC8, NPD_STAAW  ;  Q5HM33, NPD_STAEQ  ;  Q8CNF4, NPD_STAES  ;
DR   Q4JBN2, NPD_SULAC  ;  Q974M6, NPD_SULTO  ;  Q67KQ0, NPD_SYMTH  ;
DR   Q5JG47, NPD_THEKO  ;  Q9WYW0, NPD_THEMA  ;  C6A243, NPD_THESM  ;
DR   Q72IV5, NPD_THET2  ;  Q5SIH7, NPD_THET8  ;  B5YJW3, NPD_THEYD  ;
DR   Q73KE1, NPD_TREDE  ;  Q9KRX4, NPD_VIBCH  ;  Q87PH8, NPD_VIBPA  ;
DR   Q8D9J9, NPD_VIBVU  ;  Q7MKT7, NPD_VIBVY  ;  Q8PQK3, NPD_XANAC  ;
DR   Q4UZX0, NPD_XANC8  ;  B0RM75, NPD_XANCB  ;  Q8PDM9, NPD_XANCP  ;
DR   Q8ZFR1, NPD_YERPE  ;  Q669P6, NPD_YERPS  ;  Q9FE17, SIR1_ARATH ;
DR   Q96EB6, SIR1_HUMAN ;  Q923E4, SIR1_MOUSE ;  A0A0G2JZ79, SIR1_RAT   ;
DR   Q95Q89, SIR24_CAEEL;  Q54QE6, SIR2A_DICDI;  Q54LF0, SIR2B_DICDI;
DR   Q8IKW2, SIR2B_PLAF7;  Q54P49, SIR2C_DICDI;  Q54GV7, SIR2D_DICDI;
DR   Q55DB0, SIR2E_DICDI;  Q60L58, SIR2_CAEBR ;  Q21921, SIR2_CAEEL ;
DR   O59923, SIR2_CANAL ;  Q6FWI7, SIR2_CANGA ;  Q7ZVK3, SIR2_DANRE ;
DR   Q757M7, SIR2_EREGS ;  Q8IXJ6, SIR2_HUMAN ;  P33294, SIR2_KLULA ;
DR   Q25337, SIR2_LEIMA ;  Q4R834, SIR2_MACFA ;  Q8VDQ8, SIR2_MOUSE ;
DR   Q5RBF1, SIR2_PONAB ;  Q5RJQ4, SIR2_RAT   ;  O94640, SIR2_SCHPO ;
DR   Q57V41, SIR2_TRYB2 ;  P06700, SIR2_YEAST ;  Q9NTG7, SIR3_HUMAN ;
DR   Q8R104, SIR3_MOUSE ;  Q20480, SIR41_CAEEL;  Q20481, SIR42_CAEEL;
DR   Q94AQ6, SIR4_ARATH ;  F4P804, SIR4_BATDJ ;  Q1JQC6, SIR4_BOVIN ;
DR   Q8IRR5, SIR4_DROME ;  Q9Y6E7, SIR4_HUMAN ;  Q4QB33, SIR4_LEIMA ;
DR   A9UVV1, SIR4_MONBE ;  Q8R216, SIR4_MOUSE ;  Q57YZ9, SIR4_TRYB2 ;
DR   A0A0J9UVG7, SIR5_FUSO4 ;  A0A250YGJ5, SIR6_CASCN ;  Q9VH08, SIR6_DROME ;
DR   Q8N6T7, SIR6_HUMAN ;  A0A2K5TU92, SIR6_MACFA ;  P59941, SIR6_MOUSE ;
DR   Q0P595, SIR7_BOVIN ;  Q9VAQ1, SIR7_DROME ;  Q9NRC8, SIR7_HUMAN ;
DR   Q8BKJ9, SIR7_MOUSE ;  B2RZ55, SIR7_RAT   ;  Q9VK34, SIRT1_DROME;
DR   Q9I7I7, SIRT2_DROME;  B8ARK7, SRT1_ORYSI ;  Q7XWV4, SRT1_ORYSJ ;
//