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ENZYME entry: EC 2.3.1.296

Accepted Name
Omega-hydroxyceramide transacylase.
Reaction catalysed
A linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide <=> a diacyl-sn-glycerol + a linoleate-esterified acylceramide
Comment(s)
  • The enzyme participates in the production of acylceramides in the stratum corneum, the outermost layer of the epidermis.
  • Acylceramides are crucial components of the skin permeability barrier.
Cross-references
BRENDA2.3.1.296
EC2PDB2.3.1.296
ExplorEnz2.3.1.296
PRIAM enzyme-specific profiles2.3.1.296
KEGG Ligand Database for Enzyme Nomenclature2.3.1.296
IUBMB Enzyme Nomenclature2.3.1.296
IntEnz2.3.1.296
MEDLINEFind literature relating to 2.3.1.296
MetaCyc2.3.1.296
Rhea expert-curated reactions2.3.1.296
UniProtKB/Swiss-Prot
Q8N8W4, PLPL1_HUMAN;  Q3V1D5, PLPL1_MOUSE;  

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