ID   2.3.1.299
DE   sphingoid base N-stearoyltransferase.
AN   mammalian ceramide synthase 1.
CA   a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base +
CA   CoA + H(+).
CC   -!- Mammals have six ceramide synthases that exhibit relatively strict
CC       specificity regarding the chain-length of their acyl-CoA substrates.
CC   -!- Ceramide synthase 1 (CERS1) is structurally and functionally
CC       distinctive from all other CERS enzymes, and is specific for
CC       stearoyl-CoA as the acyl donor.
CC   -!- It can use multiple sphingoid bases including sphinganine,
CC       sphingosine, and phytosphingosine.
DR   P27544, CERS1_HUMAN;  P27545, CERS1_MOUSE;
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