ID   2.3.1.305
DE   acyl-[acyl-carrier protein]--UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-
DE   glucopyranose N-acyltransferase.
CA   a (3R)-hydroxyacyl-[ACP] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-
CA   glucopyranose = a UDP-2-acetamido-3-{[(3R)-3-hydroxyacyl]amino}-2,3-
CA   dideoxy-alpha-D-glucopyranose + H(+) + holo-[ACP].
CC   -!- The enzyme is found in bacterial species whose lipid A contains 2,3-
CC       diamino-2,3-dideoxy-D-glucopyranose.
CC   -!- Some enzymes, such as that from Leptospira interrogans, are highly
CC       specific for 2,3-diamino-2,3-dideoxy-D-glucopyranose, while others,
CC       such as the enzyme from Acidithiobacillus ferrooxidans, are also able
CC       to accept UDP-N-acetyl-alpha-D-glucosamine (cf. EC 2.3.1.129).
CC   -!- The enzymes from different organisms also differ in their specificity
CC       for the acyl donor. The enzyme from L. interrogans is highly specific
CC       for (3R)-3-hydroxydodecanoyl-[acyl-carrier protein], while that from
CC       Mesorhizobium loti functions almost equally well with 10-, 12-,
CC       and 14-carbon 3-hydroxyacyl-[acyl-carrier protein]s.
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