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ENZYME

ENZYME entry: EC 2.3.1.325

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.325
Accepted Name
17,18-epoxy-17-hydroxycur-19-ene N-malonyltransferase
Reaction catalysed
17,18-epoxy-17-hydroxycur-19-ene + malonyl-CoA = prestrychnine + CoA
Comment(s)
  • The enzyme, characterized from the tree Strychnos nux-vomica, catalyzes the last step in the biosynthesis of strychnine.
  • The product, prestrychnine, undergoes a slow spontaneous decarboxylation and cyclization, forming strychnine.
Cross-references
BRENDA2.3.1.325
EC2PDB2.3.1.325
ExplorEnz2.3.1.325
KEGG Ligand Database for Enzyme Nomenclature2.3.1.325
IUBMB Enzyme Nomenclature2.3.1.325
MEDLINEFind literature relating to 2.3.1.325
MetaCyc2.3.1.325
Rhea expert-curated reactions2.3.1.325
UniProtKB/Swiss-Prot
P0DO84, AT_STRNX

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