ID   2.3.1.37
DE   5-aminolevulinate synthase.
AN   5-aminolevulinic acid synthase.
AN   ALAS.
AN   delta-ALA synthetase.
AN   delta-aminolevulinate synthase.
CA   succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA.
CC   -!- A pyridoxal 5'-phosphate protein.
CC   -!- The enzyme, which catalyzes the first reaction of a tetrapyrrole
CC       biosynthesis pathway, is found in alphaproteobacteria and most
CC       eukaryotes, except plants.
CC   -!- A genetically distinct form (ALAS2) is found in erythrocytes.
CC   -!- The enzyme is also found in some bacteriophages from aquatic
CC       environments.
DR   Q3ZC31, HEM0_BOVIN ;  Q06965, HEM0_CERS4 ;  P18080, HEM0_CHICK ;
DR   Q9YHT4, HEM0_DANRE ;  Q9XT75, HEM0_DELLE ;  P22557, HEM0_HUMAN ;
DR   P08680, HEM0_MOUSE ;  P43090, HEM0_OPSTA ;  Q5R557, HEM0_PONAB ;
DR   Q63147, HEM0_RAT   ;  Q92403, HEM1_AGABI ;  P26505, HEM1_AGRRD ;
DR   A6QLI6, HEM1_BOVIN ;  P08262, HEM1_BRADU ;  O94069, HEM1_CANAL ;
DR   Q6FXE3, HEM1_CANGA ;  Q04512, HEM1_CERS4 ;  P07997, HEM1_CHICK ;
DR   Q6BX71, HEM1_DEBHA ;  Q9XS79, HEM1_DELLE ;  P38092, HEM1_EMENI ;
DR   Q75DX7, HEM1_EREGS ;  P13196, HEM1_HUMAN ;  P78698, HEM1_KLULA ;
DR   Q8VC19, HEM1_MOUSE ;  Q7RVY5, HEM1_NEUCR ;  P43091, HEM1_OPSTA ;
DR   P43089, HEM1_PARDP ;  Q5R9R9, HEM1_PONAB ;  P13195, HEM1_RAT   ;
DR   P08080, HEM1_RHIME ;  P18079, HEM1_RHOCB ;  Q1RIV2, HEM1_RICBR ;
DR   Q92G23, HEM1_RICCN ;  Q4UJV4, HEM1_RICFE ;  Q9ZCB8, HEM1_RICPR ;
DR   Q68VS3, HEM1_RICTY ;  O14092, HEM1_SCHPO ;  Q6CCW0, HEM1_YARLI ;
DR   P09950, HEM1_YEAST ;
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