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ENZYME

ENZYME entry: EC 2.3.1.45

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.45
Accepted Name
N-acetylneuraminate 9-O-acetyltransferase
Alternative Name(s)
glycoprotein 7(9)-O-acetyltransferase
N-acetylneuraminate 7,8-O-acetyltransferase
N-acetylneuraminate 7-O(or 9-O)-acetyltransferase
sialate O-acetyltransferase
Reaction catalysed
CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-9-O-acetyl-beta-neuraminate + CoA
Comment(s)
  • The enzyme, found in animals, is essential for the formation of acetylated sialoglycans.
  • The acetyl group has been shown to spontaneously move between the 9-O, 8-O, and 7-O positions of the neuraminate, with 9-O acetylation being most favoured.
Cross-references
BRENDA2.3.1.45
EC2PDB2.3.1.45
ExplorEnz2.3.1.45
KEGG Ligand Database for Enzyme Nomenclature2.3.1.45
IUBMB Enzyme Nomenclature2.3.1.45
MEDLINEFind literature relating to 2.3.1.45
MetaCyc2.3.1.45
Rhea expert-curated reactions2.3.1.45
UniProtKB/Swiss-Prot
Q1LW89, CASD1_DANREQ96PB1, CASD1_HUMANQ7TN73, CASD1_MOUSE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-