ID   2.3.1.65
DE   bile acid-CoA:amino acid N-acyltransferase.
AN   amino acid N-choloyltransferase.
AN   BACAT.
AN   BAT.
AN   cholyl-CoA:taurine N-acyltransferase.
AN   cholyl-CoA glycine-taurine N-acyltransferase.
AN   glycine N-choloyltransferase.
AN   glycine--taurine N-acyltransferase.
CA   choloyl-CoA + glycine = CoA + glycocholate + H(+).
CC   -!- Also acts on CoA derivatives of other bile acids.
CC   -!- Taurine and 2-fluoro-beta-alanine can act as substrates, but more
CC       slowly.
CC   -!- Can also conjugate fatty acids to glycine and can act as a very-long-
CC       chain acyl-CoA thioesterase.
CC   -!- Bile-acid--amino-acid conjugates serve as detergents in the
CC       gastrointestinal tract, solubilizing long chain fatty acids, mono-
CC       and diglycerides, fat-soluble vitamins and cholesterol.
CC   -!- This is the second enzyme in a two-step process leading to the
CC       conjugation of bile acids with amino acids; the first step is the
CC       conversion of bile acids into their acyl-CoA thioesters, which is
CC       catalyzed by EC 6.2.1.7.
DR   Q14032, BAAT_HUMAN ;  Q91X34, BAAT_MOUSE ;  Q63276, BAAT_RAT   ;
//