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ENZYME

ENZYME entry: EC 2.3.1.75

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.75
Accepted Name
long-chain-alcohol O-fatty-acyltransferase
Alternative Name(s)
wax-ester synthase
wax synthase
Reaction catalysed
a long chain fatty alcohol + a fatty acyl-CoA = a long-chain alcohol wax ester + CoA
Comment(s)
  • The enzyme transfers acyl residues from acyl-CoA to long-chain alcohols, forming wax esters.
  • Wax esters have diverse biological functions in bacteria, insects, mammals, and terrestrial plants.
  • The enzyme from the plant Simmondsia chinensis (jojoba) prefers acyl residues of chain-length C18 to C20 and its preferred acceptor is (11Z)-icos-11-en-1-ol.
  • cf. EC 2.3.1.332.
Cross-references
BRENDA2.3.1.75
EC2PDB2.3.1.75
ExplorEnz2.3.1.75
KEGG Ligand Database for Enzyme Nomenclature2.3.1.75
IUBMB Enzyme Nomenclature2.3.1.75
MEDLINEFind literature relating to 2.3.1.75
MetaCyc2.3.1.75
Rhea expert-curated reactions2.3.1.75
UniProtKB/Swiss-Prot
Q58HT5, AWAT1_HUMANA2ADU9, AWAT1_MOUSEQ6E213, AWAT2_HUMAN
Q6E1M8, AWAT2_MOUSEP9WKC6, TGS2_MYCTOP9WKC7, TGS2_MYCTU
Q9FJ72, WAXS1_ARATHQ9XGY6, WAXS1_SIMCHQ9FJ73, WAXS2_ARATH
Q9FJ74, WAXS3_ARATHQ9FJ75, WAXS4_ARATHQ9FJ76, WAXS5_ARATH
Q9FJ77, WAXS6_ARATHQ9FJ78, WAXS7_ARATHQ9LNL1, WAXS8_ARATH
Q4PT07, WAXS9_ARATHQ3ED15, WAXSA_ARATHQ9FGN1, WAXSB_ARATH
Q9FK04, WSD10_ARATHQ5KS41, WSD11_ARATHQ93ZR6, WSD1_ARATH
Q9C7H4, WSD2_ARATHF4IU14, WSD3_ARATHQ9M3B3, WSD4_ARATH
Q9M3B2, WSD5_ARATHQ9M3B1, WSD6_ARATHQ94CK0, WSD7_ARATH
Q9FFE8, WSD8_ARATHQ9FK89, WSD9_ARATHQ8GGG1, WSD_ACIAD

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-