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ENZYME

ENZYME entry: EC 2.3.1.81

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.81
Accepted Name
aminoglycoside N(3)-acetyltransferase
Alternative Name(s)
3-aminoglycoside acetyltransferase
aminoglycoside 3-N-acetyltransferase
Reaction catalysed
a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3)-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)
Comment(s)
  • A wide range of antibiotics containing the 2-deoxystreptamine ring can act as acceptor, including gentamicin, kanamycin, tobramycin, neomycin and apramycin.
  • Different from EC 2.3.1.60.
Cross-references
BRENDA2.3.1.81
EC2PDB2.3.1.81
ExplorEnz2.3.1.81
KEGG Ligand Database for Enzyme Nomenclature2.3.1.81
IUBMB Enzyme Nomenclature2.3.1.81
MEDLINEFind literature relating to 2.3.1.81
MetaCyc2.3.1.81
Rhea expert-curated reactions2.3.1.81
UniProtKB/Swiss-Prot
P13246, AAC31_SALSPP0A255, AAC32_SALSPQ01515, AAC3_SERMA
P29807, AACC2_ACIBAP0A256, AACC3_ENTCLP29808, AACC3_PSEAI
P08988, AACC4_SALSPP30180, AACC7_STREYP29809, AACC8_STRFR
P29810, AACC9_MICCH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-