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ENZYME entry: EC 2.3.1.n7

Accepted Name
1-acylglycerophosphoethanolamine O-acyltransferase.
Alternative Name(s)
Lysophosphatidylethanolamine acyltransferase.
Reaction catalysed
Acyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine <=> CoA + 1,2-diacyl-sn-glycero-3-phosphoethanolamine
Comment(s)
  • The enzyme mediates the conversion of lysophosphatidylethanolamine into phosphatidylethanolamine.
  • The enzyme also catalyzes the acylation of lysophosphatidylserine into phosphatidylserine (cf. EC 2.3.1.n6).
  • Prefers oleoyl-CoA as the acyl donor.
Cross-references
UniProtKB/Swiss-Prot
Q08548, ALE1_YEAST;  Q8L7R3, LPCT1_ARATH;  Q8S8S2, LPCT2_ARATH;  
Q643R3, LPCT4_HUMAN;  Q6NVG1, LPCT4_MOUSE;  Q6DCK1, LPCT4_XENLA;  
Q28C60, LPCT4_XENTR;  F4IDU4, MBOA1_ARATH;  Q6ZNC8, MBOA1_HUMAN;  
Q8BH98, MBOA1_MOUSE;  Q9CAN8, MBOA2_ARATH;  Q5ZKL6, MBOA2_CHICK;  
Q6ZWT7, MBOA2_HUMAN;  Q8R3I2, MBOA2_MOUSE;  Q3T1J2, MBOA2_RAT;  
Q3SZL3, MBOA5_BOVIN;  O01925, MBOA5_CAEEL;  Q6P1A2, MBOA5_HUMAN;  
Q91V01, MBOA5_MOUSE;  Q5FVN0, MBOA5_RAT;  Q6NN55, MBOA6_DROME;  
Q9VMD5, MBOA7_DROME;  P33333, PLSC_YEAST;  

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