A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.3.2.12

Accepted Name
Peptidyltransferase.
Reaction catalysed
Peptidyl-tRNA(1) + aminoacyl-tRNA(2) <=> tRNA(1) + peptidyl(aminoacyl-tRNA(2))
Comment(s)
  • The enzyme is a ribozyme.
  • Two non-equivlant ribonucleoprotein subunits operate in non-concerted fashion in peptide elongation.
  • The small subunit forms the mRNA-binding machinery and decoding center, the large subunit performs the main ribosomal catalytic function in the peptidyl-transferase center.
Cross-references
BRENDA2.3.2.12
EC2PDB2.3.2.12
ExplorEnz2.3.2.12
PRIAM enzyme-specific profiles2.3.2.12
KEGG Ligand Database for Enzyme Nomenclature2.3.2.12
IUBMB Enzyme Nomenclature2.3.2.12
IntEnz2.3.2.12
MEDLINEFind literature relating to 2.3.2.12
MetaCyc2.3.2.12

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-