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ENZYME entry: EC 2.3.2.19

Accepted Name
ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl- carrier protein] 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase.
Reaction catalysed
4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + ribostamycin <=> gamma-L-glutamyl-butirosin B + H(+) + holo-[BtrI ACP]
Comment(s)
  • The enzyme attaches the side chain of the aminoglycoside antibiotics of the butirosin family.
  • The side chain confers resistance against several aminoglycoside- modifying enzymes.
Cross-references
BRENDA2.3.2.19
EC2PDB2.3.2.19
ExplorEnz2.3.2.19
PRIAM enzyme-specific profiles2.3.2.19
KEGG Ligand Database for Enzyme Nomenclature2.3.2.19
IUBMB Enzyme Nomenclature2.3.2.19
IntEnz2.3.2.19
MEDLINEFind literature relating to 2.3.2.19
MetaCyc2.3.2.19
Rhea expert-curated reactions2.3.2.19
UniProtKB/Swiss-Prot
Q4H4E9, BTRH_NIACI

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