ID 2.3.2.20 DE cyclo(L-leucyl-L-phenylalanyl) synthase. CA L-leucyl-tRNA(Leu) + L-phenylalanyl-tRNA(Phe) = cyclo(L-phenylalanyl-L- CA leucyl) + H(+) + tRNA(Leu) + tRNA(Phe). CC -!- The reaction proceeds following a ping-pong mechanism forming a CC covalent intermediate between an active site serine and the CC L-phenylalanine residue. CC -!- The protein, found in the bacterium Streptomyces noursei, also forms CC cyclo(L-phenylalanyl-L-phenylalanyl), cyclo(L-methionyl-L- CC phenylalanyl), cyclo(L-phenylalanyl-L-tyrosyl) and cyclo(L-methionyl- CC L-tyrosyl). DR Q8GED7, CLPS_STRNR ; //