ID 2.3.2.22 DE cyclo(L-leucyl-L-leucyl) synthase. AN cyclodileucine synthase. CA 2 L-leucyl-tRNA(Leu) = cyclo(L-leucyl-L-leucyl) + 2 H(+) + 2 tRNA(Leu). CC -!- The reaction proceeds following a ping-pong mechanism forming a CC covalent intermediate between an active site serine and the first CC L-leucine residue. CC -!- The proteins from bacteria of the genus Bacillus also form small CC amounts of cyclo(L-phenylalanyl-L-leucyl) and cyclo(L-leucyl-L- CC methionyl). DR Q65EX3, CDLS_BACLD ; O34351, CDLS_BACSU ; Q4JVS0, CDLS_CORJK ; DR Q7N9M5, CDLS_PHOLL ; Q4L2X9, CDLS_STAHJ ; //