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ENZYME

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ENZYME entry: EC 2.3.2.25

Accepted Name
N-terminal E2 ubiquitin-conjugating enzyme
Alternative Name(s)
N-terminal ubiquitin-conjugating enzyme E2
Reaction catalysed
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein]
Comment(s)
  • The enzyme ubiquitinylates the N-terminus of the acceptor protein.
  • It is not reactive toward free lysine.
Cross-references
BRENDA2.3.2.25
EC2PDB2.3.2.25
ExplorEnz2.3.2.25
PRIAM enzyme-specific profiles2.3.2.25
KEGG Ligand Database for Enzyme Nomenclature2.3.2.25
IUBMB Enzyme Nomenclature2.3.2.25
IntEnz2.3.2.25
MEDLINEFind literature relating to 2.3.2.25
MetaCyc2.3.2.25
Rhea expert-curated reactions2.3.2.25
UniProtKB/Swiss-Prot
Q4VBH4, UB2WA_DANREQ1JPX4, UB2WB_DANREA6H795, UBE2W_BOVIN
Q9XWF6, UBE2W_CAEELQ55EY8, UBE2W_DICDIQ96B02, UBE2W_HUMAN
Q8VDW4, UBE2W_MOUSEB5DEI4, UBE2W_RATQ28FC1, UBE2W_XENTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-