ID 2.3.2.33 DE RCR-type E3 ubiquitin transferase. AN MYCBP2. AN PHR1. CA [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor CA protein]-L-threonine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + CA [acceptor protein]-3-O-ubiquitinyl-L-threonine. CC -!- RCR-type E3 ubiquitin transferases is a class of RING-type E3 CC ubiquitin transferase (see EC 2.3.2.27) that mediates ubiquitination CC of acceptor proteins via an internal cysteine residue. CC -!- The RING1 domain binds an EC 2.3.2.23 and transfers the ubiquitin CC that is bound to it to an internal cysteine residue on a mediator CC loop of the RCR-type ligase. CC -!- The ubiquitin may be transferred to a second internal cysteine before CC the transfer of the ubiquitin from the RCR-type ligase to the CC substrate. DR Q9NB71, HIW_DROME ; F1RD40, MYCB2_DANRE; O75592, MYCB2_HUMAN; DR Q7TPH6, MYCB2_MOUSE; Q17551, RPM1_CAEEL ; //