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ENZYME

ENZYME entry: EC 2.3.2.37

PURL: https://purl.expasy.org/enzyme/EC/2.3.2.37
Accepted Name
ergosteryl-3beta-O-L-aspartate synthase
Reaction catalysed
L-aspartyl-tRNA(Asp) + ergosterol = 1-(ergostan-3beta-yl)-L-aspartate + tRNA(Asp)
Comment(s)
  • The enzyme, detected in fungal species that belong to the Ascomycota and Basidiomycota phyla and characterized from Aspergillus fumigatus, is bifunctional.
  • The AspRS domain catalyzes the transfer of L-aspartate to tRNA(Asp) (EC 6.1.1.12), while the second domain carries out the transfer of L-aspartate to the 3beta-hydroxyl of ergosterol.
Cross-references
BRENDA2.3.2.37
EC2PDB2.3.2.37
ExplorEnz2.3.2.37
KEGG Ligand Database for Enzyme Nomenclature2.3.2.37
IUBMB Enzyme Nomenclature2.3.2.37
MEDLINEFind literature relating to 2.3.2.37
MetaCyc2.3.2.37
Rhea expert-curated reactions2.3.2.37

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-