ENZYME entry: EC 2.3.2.5
Accepted Name |
Glutaminyl-peptide cyclotransferase.
|
Alternative Name(s) |
Glutaminyl cyclase. |
Glutaminyl-tRNA cyclotransferase. |
Reaction catalysed |
L-glutaminyl-peptide <=> 5-oxoprolyl-peptide + NH(3) |
Comment(s) |
- Involved in the formation of thyrotropin-releasing hormone and other
biologically active peptides containing N-terminal pyroglutamyl
residues.
- The enzyme from papaya also acts on glutaminyl-tRNA.
|
Cross-references |
BRENDA | 2.3.2.5 |
EC2PDB | 2.3.2.5 |
ExplorEnz | 2.3.2.5 |
PRIAM enzyme-specific profiles | 2.3.2.5 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.2.5 |
IUBMB Enzyme Nomenclature | 2.3.2.5 |
IntEnz | 2.3.2.5 |
MEDLINE | Find literature relating to 2.3.2.5 |
MetaCyc | 2.3.2.5 |
Rhea expert-curated reactions | 2.3.2.5 |
UniProtKB/Swiss-Prot |
Q0V8G3, QPCTL_BOVIN; | Q9NXS2, QPCTL_HUMAN; | Q4R942, QPCTL_MACFA; |
Q8BH73, QPCTL_MOUSE; | Q84WV9, QPCT_ARATH; | A7ISW2, QPCT_BOIDE; |
A7ISW1, QPCT_BOIIR; | Q9YIB5, QPCT_BOTJA; | Q28120, QPCT_BOVIN; |
P0CV92, QPCT_CROAT; | Q54B14, QPCT_DICDI; | Q90YA8, QPCT_GLOBL; |
Q16769, QPCT_HUMAN; | B7QK46, QPCT_IXOSC; | Q9CYK2, QPCT_MOUSE; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-