A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.3.3.1
| Accepted Name |
|---|
| Citrate (Si)-synthase.
|
| Alternative Name(s) |
|---|
| (R)-citrate synthase. |
| Citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO->acetyl-CoA). |
| Reaction catalysed |
|---|
| Acetyl-CoA + H(2)O + oxaloacetate <=> citrate + CoA |
| Comment(s) |
|---|
- The stereospecificity of this enzyme is opposite to that of
EC 2.3.3.3, which is found in some anaerobes.
- Citrate synthase for which the stereospecificity with respect to C(2)
of oxaloacetate has not been established are included in EC 2.3.3.16.
- Formerly EC 4.1.3.7.
|
| Cross-references |
|---|
| PROSITE | PDOC00422 |
| BRENDA | 2.3.3.1 |
| EC2PDB | 2.3.3.1 |
| ExplorEnz | 2.3.3.1 |
| PRIAM enzyme-specific profiles | 2.3.3.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.3.3.1 |
| IUBMB Enzyme Nomenclature | 2.3.3.1 |
| IntEnz | 2.3.3.1 |
| MEDLINE | Find literature relating to 2.3.3.1 |
| MetaCyc | 2.3.3.1 |
| UniProtKB/Swiss-Prot |
| P00890, CISY1_YEAST; | P43635, CISY3_YEAST; | Q0GNE1, CISY_AMBCR; |
| Q29RK1, CISY_BOVIN; | P23007, CISY_CHICK; | Q7ZVY5, CISY_DANRE; |
| O75390, CISY_HUMAN; | Q0GNE0, CISY_IGUIG; | Q6S9V5, CISY_KAJAU; |
| Q6S9V7, CISY_KATPE; | P0C1Z2, CISY_MACFA; | Q0QEL7, CISY_MESAU; |
| Q9CZU6, CISY_MOUSE; | P00889, CISY_PIG; | Q8VHF5, CISY_RAT; |
| Q4S5X1, CISY_TETNG; | Q6S9V9, CISY_THUAL; | Q6S9V8, CISY_THUOB; |
| Q7ZWZ5, CISY_XENLA; | Q28DK1, CISY_XENTR; | Q6S9V6, CISY_XIPGL; |
|
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