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ENZYME

ENZYME entry: EC 2.3.3.1

PURL: https://purl.expasy.org/enzyme/EC/2.3.3.1
Accepted Name
citrate (Si)-synthase
Alternative Name(s)
(R)-citrate synthase
citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA]
Reaction catalysed
oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)
Comment(s)
  • The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.
  • Citrate synthase for which the stereospecificity with respect to C2 of oxaloacetate has not been established are included in EC 2.3.3.16.
  • Formerly EC 4.1.3.7.
Cross-references
BRENDA2.3.3.1
EC2PDB2.3.3.1
ExplorEnz2.3.3.1
KEGG Ligand Database for Enzyme Nomenclature2.3.3.1
IUBMB Enzyme Nomenclature2.3.3.1
MEDLINEFind literature relating to 2.3.3.1
MetaCyc2.3.3.1
Rhea expert-curated reactions2.3.3.1
UniProtKB/Swiss-Prot
P00890, CISY1_YEASTP43635, CISY3_YEASTQ0GNE1, CISY_AMBCR
Q29RK1, CISY_BOVINP23007, CISY_CHICKQ7ZVY5, CISY_DANRE
O75390, CISY_HUMANQ0GNE0, CISY_IGUIGQ6S9V5, CISY_KAJAU
Q6S9V7, CISY_KATPEP0C1Z2, CISY_MACFAQ0QEL7, CISY_MESAU
Q9CZU6, CISY_MOUSEP00889, CISY_PIGQ8VHF5, CISY_RAT
Q4S5X1, CISY_TETNGQ6S9V9, CISY_THUALQ6S9V8, CISY_THUOB
Q7ZWZ5, CISY_XENLAQ28DK1, CISY_XENTRQ6S9V6, CISY_XIPGL

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