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ENZYME

ENZYME entry: EC 2.3.3.10

Accepted Name
hydroxymethylglutaryl-CoA synthase
Alternative Name(s)
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating)
3-hydroxy-3-methylglutaryl-CoA synthase
3-hydroxy-3-methylglutaryl CoA synthetase
3-hydroxy-3-methylglutaryl coenzyme A synthase
3-hydroxy-3-methylglutaryl-coenzyme A synthase
3-hydroxy-3-methylglutaryl coenzyme A synthetase
acetoacetyl coenzyme A transacetase
beta-hydroxy-beta-methylglutaryl-CoA synthase
HMG-CoA synthase
hydroxymethylglutaryl coenzyme alpha-condensing enzyme
hydroxymethylglutaryl coenzyme A synthase
Reaction catalysed
acetoacetyl-CoA + acetyl-CoA + H2O <=> (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)
Comment(s)
Formerly EC 4.1.3.5.
Cross-references
BRENDA2.3.3.10
EC2PDB2.3.3.10
ExplorEnz2.3.3.10
PRIAM enzyme-specific profiles2.3.3.10
KEGG Ligand Database for Enzyme Nomenclature2.3.3.10
IUBMB Enzyme Nomenclature2.3.3.10
IntEnz2.3.3.10
MEDLINEFind literature relating to 2.3.3.10
MetaCyc2.3.3.10
Rhea expert-curated reactions2.3.3.10
UniProtKB/Swiss-Prot
Q4WBQ3, ER13A_ASPFUQ4WXT8, ER13B_ASPFUA0A1D8PTW6, ERG13_CANAL
K7PL94, ERG13_GANLUI1RY35, ERG13_GIBZEP54874, ERG13_SCHPO
P54839, ERG13_YEASTA0A6S5ZZ88, G431_FUSSXQ4P3F1, HCS1_USTMA
F9X3D9, HCS1_ZYMTIP54961, HMCS1_BLAGEP23228, HMCS1_CHICK
P13704, HMCS1_CRIGRQ01581, HMCS1_HUMANQ8JZK9, HMCS1_MOUSE
Q5R7Z9, HMCS1_PONABP17425, HMCS1_RATP54870, HMCS2_BLAGE
Q2KIE6, HMCS2_BOVINP54868, HMCS2_HUMANP54869, HMCS2_MOUSE
O02734, HMCS2_PIGP22791, HMCS2_RATP54872, HMCSA_DICDI
Q86HL5, HMCSB_DICDIP54873, HMCS_ARATHP54871, HMCS_CAEEL
Q9FD71, HMGCS_ENTFLD4GWR6, HMGCS_HALVD

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
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