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ENZYME

ENZYME entry: EC 2.3.3.8

PURL: https://purl.expasy.org/enzyme/EC/2.3.3.8
Accepted Name
ATP citrate synthase
Alternative Name(s)
acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating)
adenosine triphosphate citrate lyase
ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP- dephosphorylating)
ATP citrate (pro-S)-lyase
ATP-citrate (pro-S-)-lyase
ATP-citric lyase
citrate-ATP lyase
citrate cleavage enzyme
citric cleavage enzyme
Reaction catalysed
oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA
Comment(s)
  • The enzyme can be dissociated into components, two of which are identical with EC 4.1.3.34 and EC 6.2.1.18.
  • Formerly EC 4.1.3.8.
Cross-references
BRENDA2.3.3.8
EC2PDB2.3.3.8
ExplorEnz2.3.3.8
KEGG Ligand Database for Enzyme Nomenclature2.3.3.8
IUBMB Enzyme Nomenclature2.3.3.8
MEDLINEFind literature relating to 2.3.3.8
MetaCyc2.3.3.8
Rhea expert-curated reactions2.3.3.8
UniProtKB/Swiss-Prot
Q8X097, ACL1_NEUCRQ9P7W3, ACL1_SCHPOO93988, ACL1_SORMK
O13907, ACL2_SCHPOQ9SGY2, ACLA1_ARATHQ53JY8, ACLA1_ORYSJ
O22718, ACLA2_ARATHQ2QZ86, ACLA2_ORYSJO80526, ACLA3_ARATH
Q2QNG7, ACLA3_ORYSJQ9C522, ACLB1_ARATHQ93VT8, ACLB1_ORYSJ
Q9FGX1, ACLB2_ARATHQ32PF2, ACLY_BOVINP53585, ACLY_CAEEL
Q54YA0, ACLY_DICDIP53396, ACLY_HUMANQ91V92, ACLY_MOUSE
P16638, ACLY_RATQ2TCH3, ACLY_SHEEP

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-