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ENZYME entry: EC 2.4.1.109

Accepted Name
Dolichyl-phosphate-mannose--protein mannosyltransferase.
Alternative Name(s)
Dolichol phosphomannose-protein mannosyltransferase.
Dolichyl-phosphate-mannose-protein mannosyltransferase.
Reaction catalysed
Dolichyl D-mannosyl phosphate + protein <=> dolichyl phosphate + O-D-mannosylprotein
Comment(s)
  • Transfers mannosyl residues to the hydroxy of serine or threonine residues, producing cell-wall mannoproteins.
  • Acts only on long-chain alpha-dihydropolyprenyl derivatives, larger than C(35).
Cross-references
BRENDA2.4.1.109
EC2PDB2.4.1.109
ExplorEnz2.4.1.109
PRIAM enzyme-specific profiles2.4.1.109
KEGG Ligand Database for Enzyme Nomenclature2.4.1.109
IUBMB Enzyme Nomenclature2.4.1.109
IntEnz2.4.1.109
MEDLINEFind literature relating to 2.4.1.109
MetaCyc2.4.1.109
UniProtKB/Swiss-Prot
O74189, PMT1_CANAL;  O13898, PMT1_SCHPO;  P33775, PMT1_YEAST;  
Q5ADM9, PMT2_CANAL;  Q9C100, PMT2_SCHPO;  P31382, PMT2_YEAST;  
P47190, PMT3_YEAST;  Q59X23, PMT4_CANAL;  O42933, PMT4_SCHPO;  
P46971, PMT4_YEAST;  Q5ACU3, PMT5_CANAL;  P52867, PMT5_YEAST;  
Q5A688, PMT6_CANAL;  P42934, PMT6_YEAST;  Q06644, PMT7_YEAST;  
Q8NRZ6, PMT_CORGL;  L8F4Z2, PMT_MYCSE;  P9WN04, PMT_MYCTO;  
P9WN05, PMT_MYCTU;  F1QF89, POMT1_DANRE;  Q9VTK2, POMT1_DROME;  
Q2LZ62, POMT1_DROPS;  Q9Y6A1, POMT1_HUMAN;  Q8R2R1, POMT1_MOUSE;  
Q99PR0, POMT1_RAT;  F1Q8R9, POMT2_DANRE;  Q9W5D4, POMT2_DROME;  
Q29IL2, POMT2_DROPS;  Q9UKY4, POMT2_HUMAN;  Q8BGQ4, POMT2_MOUSE;  
Q20144, TMTC1_CAEEL;  Q9VQE9, TMTC1_DROME;  Q8IUR5, TMTC1_HUMAN;  
Q3UV71, TMTC1_MOUSE;  Q9V3X5, TMTC2_DROME;  Q8N394, TMTC2_HUMAN;  
Q56A06, TMTC2_MOUSE;  Q6DCD5, TMTC2_XENLA;  Q7K4B6, TMTC3_DROME;  
Q6ZXV5, TMTC3_HUMAN;  Q8BRH0, TMTC3_MOUSE;  Q9VF81, TMTC4_DROME;  
Q5T4D3, TMTC4_HUMAN;  Q8BG19, TMTC4_MOUSE;  

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