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ENZYME entry: EC 2.4.1.12

Accepted Name
cellulose synthase (UDP-forming).
Alternative Name(s)
UDP-glucose-beta-D-glucan glucosyltransferase.
UDP-glucose--beta-glucan glucosyltransferase.
UDP-glucose-cellulose glucosyltransferase.
Reaction catalysed
[(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose <=> [(1->4)-beta-D-glucosyl](n+1) + H(+) + UDP
Comment(s)
  • Involved in the synthesis of cellulose.
  • A similar enzyme utilizes GDP-glucose (cf. EC 2.4.1.29).
Cross-references
BRENDA2.4.1.12
EC2PDB2.4.1.12
ExplorEnz2.4.1.12
PRIAM enzyme-specific profiles2.4.1.12
KEGG Ligand Database for Enzyme Nomenclature2.4.1.12
IUBMB Enzyme Nomenclature2.4.1.12
IntEnz2.4.1.12
MEDLINEFind literature relating to 2.4.1.12
MetaCyc2.4.1.12
Rhea expert-curated reactions2.4.1.12
UniProtKB/Swiss-Prot
P0CW87, ACSA1_KOMXY;  Q76KJ8, ACSA1_NOVHA;  Q59167, ACSA2_NOVHA;  
P19449, BCSA1_KOMXY;  O82859, BCSA2_KOMSB;  Q9WX61, BCSA3_KOMXY;  
Q9RBJ2, BCSA4_KOMXY;  Q9WX75, BCSA5_KOMXY;  Q8X5L7, BCSA_ECO57;  
P37653, BCSA_ECOLI;  P58931, BCSA_PSEFS;  Q8Z291, BCSA_SALTI;  
Q93IN2, BCSA_SALTY;  P58932, BCSA_XANAC;  O48946, CESA1_ARATH;  
A2Y0X2, CESA1_ORYSI;  Q6AT26, CESA1_ORYSJ;  O48947, CESA2_ARATH;  
A2XN66, CESA2_ORYSI;  Q84M43, CESA2_ORYSJ;  Q941L0, CESA3_ARATH;  
Q69V23, CESA3_ORYSJ;  Q84JA6, CESA4_ARATH;  A2WV32, CESA4_ORYSI;  
Q5JN63, CESA4_ORYSJ;  Q8L778, CESA5_ARATH;  A2XNT2, CESA5_ORYSI;  
Q851L8, CESA5_ORYSJ;  Q94JQ6, CESA6_ARATH;  Q6YVM4, CESA6_ORYSJ;  
Q9SWW6, CESA7_ARATH;  Q9AV71, CESA7_ORYSJ;  Q8LPK5, CESA8_ARATH;  
Q84ZN6, CESA8_ORYSJ;  Q9SJ22, CESA9_ARATH;  A2Z1C8, CESA9_ORYSI;  
Q69P51, CESA9_ORYSJ;  Q9SKJ5, CESAA_ARATH;  Q69XK5, CESAB_ORYSJ;  
Q9U720, DCSA_DICDI;  

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