ID   2.4.1.131
DE   GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase.
CA   alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-
CA   (1->4)-alpha-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = alpha-
CA   D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-
CA   beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol +
CA   2 GDP + 2 H(+).
CC   -!- The biosynthesis of asparagine-linked glycoproteins (N-linked protein
CC       glycosylation) utilizes a dolichyl diphosphate-linked glycosyl donor,
CC       which is assembled by the series of membrane-bound
CC       glycosyltransferases that comprise the dolichol pathway.
CC   -!- ALG11 mannosyltransferase from Saccharomyces cerevisiae carries out
CC       two sequential steps in the formation of the lipid-linked core
CC       oligosaccharide, adding two mannose residues in alpha(1->2) linkages
CC       to the nascent oligosaccharide.
CC   -!- Formerly EC 2.4.1.n4.
DR   Q9XEE9, ALG11_ARATH;  P53993, ALG11_CAEEL;  Q59S72, ALG11_CANAL;
DR   Q6FWD1, ALG11_CANGA;  Q7ZW24, ALG11_DANRE;  Q6BVB2, ALG11_DEBHA;
DR   Q54DM9, ALG11_DICDI;  Q75B12, ALG11_EREGS;  Q2TAA5, ALG11_HUMAN;
DR   Q6CLD6, ALG11_KLULA;  Q3TZM9, ALG11_MOUSE;  Q8X092, ALG11_NEUCR;
DR   Q5R7Z6, ALG11_PONAB;  O74878, ALG11_SCHPO;  Q08B22, ALG11_XENLA;
DR   Q6P312, ALG11_XENTR;  Q6C9T3, ALG11_YARLI;  P53954, ALG11_YEAST;
//