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ENZYME entry: EC 2.4.1.134

Accepted Name
Galactosylxylosylprotein 3-beta-galactosyltransferase.
Alternative Name(s)
Galactosyltransferase II.
Uridine diphosphogalactose-galactosylxylose galactosyltransferase.
Reaction catalysed
UDP-alpha-D-galactose + 4-beta-D-galactosyl-O-beta-D-xylosyl-[protein] <=> UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-[protein]
Cofactor(s)
Mn(2+).
Comment(s)
Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates).
Cross-references
BRENDA2.4.1.134
EC2PDB2.4.1.134
ExplorEnz2.4.1.134
PRIAM enzyme-specific profiles2.4.1.134
KEGG Ligand Database for Enzyme Nomenclature2.4.1.134
IUBMB Enzyme Nomenclature2.4.1.134
IntEnz2.4.1.134
MEDLINEFind literature relating to 2.4.1.134
MetaCyc2.4.1.134
Rhea expert-curated reactions2.4.1.134
UniProtKB/Swiss-Prot
Q96L58, B3GT6_HUMAN;  Q91Z92, B3GT6_MOUSE;  Q9USX0, PVG3_SCHPO;  
Q9N491, SQV2_CAEEL;  

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