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ENZYME entry: EC 2.4.1.149

Accepted Name
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase.
Alternative Name(s)
beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3- acetylglucosaminyltransferase.
GnTE.
poly-N-acetyllactosamine extension enzyme.
Reaction catalysed
a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine <=> an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP
Comment(s)
  • Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on glycoproteins, glycolipids, and oligosaccharides.
  • Formerly EC 2.4.1.163.
Cross-references
BRENDA2.4.1.149
EC2PDB2.4.1.149
ExplorEnz2.4.1.149
PRIAM enzyme-specific profiles2.4.1.149
KEGG Ligand Database for Enzyme Nomenclature2.4.1.149
IUBMB Enzyme Nomenclature2.4.1.149
IntEnz2.4.1.149
MEDLINEFind literature relating to 2.4.1.149
MetaCyc2.4.1.149
Rhea expert-curated reactions2.4.1.149
UniProtKB/Swiss-Prot
Q9NY97, B3GN2_HUMAN;  Q9Z222, B3GN2_MOUSE;  Q9Y2A9, B3GN3_HUMAN;  
Q5JCS9, B3GN3_MOUSE;  Q9C0J1, B3GN4_HUMAN;  Q1RLK6, B3GN4_MOUSE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
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