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ENZYME

ENZYME entry: EC 2.4.1.153

PURL: https://purl.expasy.org/enzyme/EC/2.4.1.153
Accepted Name
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminyltransferase
Alternative Name(s)
dolichyl-phosphate acetylglucosaminyltransferase
dolichyl-phosphate alpha-N-acetylglucosaminyltransferase
Reaction catalysed
a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-phospho-di-trans,poly-cis-dolichol + UDP
Comment(s)
  • The enzyme, characterized from the methanogenic archaeon Methanococcus voltae, initiates N-linked glycosylation in that organism.
  • The enzyme differs from the eukaryotic enzyme, which leaves one additional phosphate group on the dolichyl product (cf. EC 2.7.8.15).
Cross-references
BRENDA2.4.1.153
EC2PDB2.4.1.153
ExplorEnz2.4.1.153
KEGG Ligand Database for Enzyme Nomenclature2.4.1.153
IUBMB Enzyme Nomenclature2.4.1.153
MEDLINEFind literature relating to 2.4.1.153
MetaCyc2.4.1.153
Rhea expert-curated reactions2.4.1.153
UniProtKB/Swiss-Prot
B3VA58, AGLK_METVO

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