ID   2.4.1.174
DE   glucuronylgalactosylproteoglycan 4-beta-N-
DE   acetylgalactosaminyltransferase.
AN   glucuronylgalactosylproteoglycan beta-1,4-N-
AN   acetylgalactosaminyltransferase.
AN   N-acetylgalactosaminyltransferase I.
AN   uridine diphosphoacetylgalactosamine-chondroitin
AN   acetylgalactosaminyltransferase I.
CA   3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-
CA   L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-(beta-D-
CA   GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-
CA   beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP.
CC   -!- Involved in the biosynthesis of chondroitin sulfate.
CC   -!- Key enzyme activity for the initiation of chondroitin and dermatan
CC       sulfates, transferring GalNAc to the GlcA-Gal-Gal-Xyl-Ser core.
DR   Q8TDX6, CGAT1_HUMAN;  Q8BJQ9, CGAT1_MOUSE;  Q8N6G5, CGAT2_HUMAN;
DR   Q8C1F4, CGAT2_MOUSE;  Q7Z1Z1, CHSSA_CAEEL;
//