ID   2.4.1.212
DE   hyaluronan synthase.
AN   HAS.
CA   (1) [hyaluronan](n) + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N-acetyl-
CA   beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP.
CA   (2) N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-
CA   glucuronate = [hyaluronan](n+1) + H(+) + UDP.
CC   -!- Adds GlcNAc to nascent hyaluronan when the non-reducing end is GlcA,
CC       but it adds GlcA when the non-reducing end is GlcNAc.
CC   -!- Highly specific for UDP-GlcNAc and UDP-GlcA; no copolymerization is
CC       observed if either is replaced by UDP-Glc, UDP-Gal, UDP-GalNAc or
CC       UDP-GalA.
DR   P0C0H1, HASA_STRP1 ;  P0DB60, HASA_STRP3 ;  Q5X9A9, HASA_STRP6 ;
DR   Q8NKX1, HASA_STRP8 ;  P0DB61, HASA_STRPQ ;  P0C0H0, HASA_STRPY ;
DR   Q7BLV3, HAS_PASMD  ;  Q92839, HYAS1_HUMAN;  Q61647, HYAS1_MOUSE;
DR   P13563, HYAS1_XENLA;  B1WB39, HYAS1_XENTR;  O97711, HYAS2_BOVIN;
DR   O57424, HYAS2_CHICK;  G5AY81, HYAS2_HETGA;  Q92819, HYAS2_HUMAN;
DR   P70312, HYAS2_MOUSE;  O35776, HYAS2_RAT  ;  O57427, HYAS2_XENLA;
DR   O57425, HYAS3_CHICK;  O00219, HYAS3_HUMAN;  O08650, HYAS3_MOUSE;
DR   O57426, HYAS3_XENLA;
//