ID   2.4.1.221
DE   peptide-O-fucosyltransferase.
AN   GDP-fucose protein O-fucosyltransferase.
CA   (1) L-seryl-[protein] + GDP-beta-L-fucose = 3-O-(alpha-L-fucosyl)-L-
CA   seryl-[protein] + GDP + H(+).
CA   (2) L-threonyl-[protein] + GDP-beta-L-fucose = 3-O-(alpha-L-fucosyl)-L-
CA   threonyl-[protein] + GDP + H(+).
CC   -!- The enzyme, found in animals and plants, is involved in the
CC       biosynthesis of O-fucosylated proteins.
CC   -!- In EGF domains, the attachment of fucose to serine or threonine
CC       occurs within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys.
CC   -!- The POFUT3 and POFUT4 proteins modify EMI domains.
DR   Q18014, OFUT1_CAEEL;  P83337, OFUT1_CRIGR;  Q9V6X7, OFUT1_DROME;
DR   Q9H488, OFUT1_HUMAN;  Q91ZW2, OFUT1_MOUSE;  Q6EV69, OFUT1_PANTR;
DR   Q6EV70, OFUT1_RAT  ;  Q8WR51, OFUT2_CAEEL;  Q9W589, OFUT2_DROME;
DR   Q9Y2G5, OFUT2_HUMAN;  Q8VHI3, OFUT2_MOUSE;  Q6EV56, OFUT2_PANTR;
DR   A0A509AKB8, OFUT2_PLABA;  W7K6N5, OFUT2_PLAFO;  A5K6G1, OFUT2_PLAVS;
DR   S7WCF5, OFUT2_TOXGG;  Q6A198, OFUT3_BOVIN;  Q5F2N4, OFUT3_CANLF;
DR   Q8AWB5, OFUT3_CHICK;  Q5F2N3, OFUT3_DANRE;  Q6P4F1, OFUT3_HUMAN;
DR   Q5F2L2, OFUT3_MOUSE;  Q5F2L1, OFUT3_RAT  ;  Q6NTZ6, OFUT3_XENLA;
DR   Q6A1G3, OFUT3_XENTR;  Q8AWC7, OFUT4_CHICK;  Q08C60, OFUT4_DANRE;
DR   Q495W5, OFUT4_HUMAN;  Q8BHC9, OFUT4_MOUSE;  Q5F2N2, OFUT4_ORYLA;
DR   Q68FV3, OFUT4_RAT  ;  Q70AG8, OFUT4_TAKRU;  Q6A1G2, OFUT4_XENTR;
DR   Q96301, SPY_ARATH  ;
//