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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.4.1.241

Accepted Name
Digalactosyldiacylglycerol synthase.
Alternative Name(s)
DGDG synthase.
UDP-galactose-dependent DGDG synthase.
UDP-galactose-dependent digalactosyldiacylglycerol synthase.
UDP-galactose:MGDG galactosyltransferase.
Reaction catalysed
UDP-alpha-D-galactose + 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol <=> UDP + 3-(alpha-D-galactosyl-(1->6)-beta-D-galactosyl)-1,2-diacyl-sn-glycerol
Cofactor(s)
Mg(2+).
Comment(s)
  • Diacylglycerol cannot serve as an acceptor molecule for galactosylation as in the reaction catalyzed by EC 2.4.1.46.
  • When phosphate is limiting, phospholipids in plant membranes are reduced but these are replaced, at least in part, by the glycolipids digalactosyldiacylglycerol (DGDG) and sulfoquinovosyldiacylglycerol.
  • While both DGD1 and DGD2 are increased under phosphate-limiting conditions, DGD2 does not contribute significantly under optimal growth conditions.
  • DGD2 is responsible for the synthesis of DGDG molecular species that are rich in C16 fatty acids at sn-1 of diacylglycerol whereas DGD1 leads to molecular species rich in C18 fatty acids.
  • The enzyme has been localized to the outer side of chloroplast envelope membranes.
Cross-references
BRENDA2.4.1.241
EC2PDB2.4.1.241
ExplorEnz2.4.1.241
PRIAM enzyme-specific profiles2.4.1.241
KEGG Ligand Database for Enzyme Nomenclature2.4.1.241
IUBMB Enzyme Nomenclature2.4.1.241
IntEnz2.4.1.241
MEDLINEFind literature relating to 2.4.1.241
MetaCyc2.4.1.241
UniProtKB/Swiss-Prot
Q9S7D1, DGDG1_ARATH;  Q6DW74, DGDG1_LOTJA;  Q6DW76, DGDG1_SOYBN;  
Q8W1S1, DGDG2_ARATH;  Q6DW73, DGDG2_LOTJA;  Q6DW75, DGDG2_SOYBN;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
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