ID   2.4.1.245
DE   alpha,alpha-trehalose synthase.
AN   trehalose synthase.
AN   trehalose synthetase.
CA   an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate +
CA   alpha,alpha-trehalose + H(+).
CC   -!- The enzyme-catalyzed reaction is reversible.
CC   -!- In the reverse direction to that shown above, the enzyme is specific
CC       for alpha,alpha-trehalose as substrate, as it cannot use alpha- or
CC       beta-paranitrophenyl glucosides, maltose, sucrose, lactose or
CC       cellobiose.
CC   -!- While the enzymes from the thermophilic bacterium Rubrobacter
CC       xylanophilus and the hyperthermophilic archaeon Pyrococcus horikoshii
CC       can use ADP-, UDP- and GDP-alpha-D-glucose to the same extent, that
CC       from the hyperthermophilic archaeon Thermococcus litoralis has a
CC       marked preference for ADP-alpha-D-glucose and that from the
CC       hyperthermophilic archaeon Thermoproteus tenax has a marked
CC       preference for UDP-alpha-D-glucose.
CC   -!- Formerly EC 2.4.1.n1.
DR   Q9HH00, TRET_PYRFU ;  O58762, TRET_PYRHO ;  Q1ARU5, TRET_RUBXD ;
DR   Q7LYW5, TRET_THELN ;
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