A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.4.1.283
| Accepted Name |
|---|
| 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase.
|
| Reaction catalysed |
|---|
| UDP-N-acetyl-alpha-D-glucosamine + 2-deoxystreptamine <=> UDP + 2'-N-acetylparomamine |
| Comment(s) |
|---|
- Involved in the biosynthetic pathways of several clinically important
aminocyclitol antibiotics, including kanamycin, butirosin, neomycin
and ribostamycin.
- Unlike the enzyme from the bacterium Streptomyces kanamyceticus,
which can also accept UDP-D-glucose (cf. EC 2.4.1.284), the enzyme
from Bacillus circulans can only accept UDP-N-acetyl-alpha-D-
glucosamine.
|
| Cross-references |
|---|
| BRENDA | 2.4.1.283 |
| EC2PDB | 2.4.1.283 |
| ExplorEnz | 2.4.1.283 |
| PRIAM enzyme-specific profiles | 2.4.1.283 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.283 |
| IUBMB Enzyme Nomenclature | 2.4.1.283 |
| IntEnz | 2.4.1.283 |
| MEDLINE | Find literature relating to 2.4.1.283 |
| MetaCyc | 2.4.1.283 |
| UniProtKB/Swiss-Prot |
|
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