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ENZYME

ENZYME entry: EC 2.4.1.287

Accepted Name
rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,4/1,5- galactofuranosyltransferase
Alternative Name(s)
arabinogalactan galactofuranosyl transferase 1
Reaction catalysed
alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose <=> beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 H(+) + 2 UDP
Comment(s)
  • Isolated from Mycobacterium tuberculosis and M.smegmatis, the enzyme has dual beta-(1->4) and beta-(1->5) transferase action.
  • Involved in the formation of the cell wall in mycobacteria.
Cross-references
BRENDA2.4.1.287
EC2PDB2.4.1.287
ExplorEnz2.4.1.287
PRIAM enzyme-specific profiles2.4.1.287
KEGG Ligand Database for Enzyme Nomenclature2.4.1.287
IUBMB Enzyme Nomenclature2.4.1.287
IntEnz2.4.1.287
MEDLINEFind literature relating to 2.4.1.287
MetaCyc2.4.1.287
Rhea expert-curated reactions2.4.1.287
UniProtKB/Swiss-Prot
A0R5Z2, GLFT1_MYCS2P9WMX2, GLFT1_MYCTOP9WMX3, GLFT1_MYCTU

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