ENZYME entry: EC 2.4.1.287

PURL: https://purl.expasy.org/enzyme/EC/2.4.1.287

Accepted Name

rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,4/1,5- galactofuranosyltransferase

Alternative Name(s)

arabinogalactan galactofuranosyl transferase 1

Reaction catalysed

alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP + 2 H(+)

Comment(s)

Isolated from Mycobacterium tuberculosis and M.smegmatis, the enzyme has dual beta-(1->4) and beta-(1->5) transferase action.
Involved in the formation of the cell wall in mycobacteria.

Cross-references

BRENDA

2.4.1.287

EC2PDB

2.4.1.287

ExplorEnz

2.4.1.287

KEGG Ligand Database for Enzyme Nomenclature

2.4.1.287

IUBMB Enzyme Nomenclature

2.4.1.287

MEDLINE

Find literature relating to 2.4.1.287

MetaCyc

2.4.1.287

Rhea expert-curated reactions

2.4.1.287

UniProtKB/Swiss-Prot

A0R5Z2, GLFT1_MYCS2

P9WMX2, GLFT1_MYCTO

P9WMX3, GLFT1_MYCTU

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-