ENZYME entry: EC 2.4.1.301
Accepted Name |
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase.
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Reaction catalysed |
- UDP-alpha-D-kanosamine + 2'-deamino-2'-hydroxyneamine <=> UDP + kanamycin A
- UDP-alpha-D-kanosamine + neamine <=> UDP + kanamycin B
- UDP-alpha-D-kanosamine + paromamine <=> UDP + kanamycin C
- UDP-alpha-D-kanosamine + 2'-deamino-2'-hydroxyparomamine <=> UDP + kanamycin X
|
Comment(s) |
- Involved in the biosynthetic pathway of kanamycins.
- The enzyme characterized from the bacterium Streptomyces
kanamyceticus can also accept UDP-alpha-D-glucose with lower
efficiency.
|
Cross-references |
BRENDA | 2.4.1.301 |
EC2PDB | 2.4.1.301 |
ExplorEnz | 2.4.1.301 |
PRIAM enzyme-specific profiles | 2.4.1.301 |
KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.301 |
IUBMB Enzyme Nomenclature | 2.4.1.301 |
IntEnz | 2.4.1.301 |
MEDLINE | Find literature relating to 2.4.1.301 |
MetaCyc | 2.4.1.301 |
Rhea expert-curated reactions | 2.4.1.301 |
UniProtKB/Swiss-Prot |
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