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ENZYME entry: EC 2.4.1.327

Accepted Name
Aclacinomycin-T 2-deoxy-L-fucose transferase.
Reaction catalysed
dTDP-2-deoxy-beta-L-fucose + aclacinomycin T <=> dTDP + aclacinomycin S
Comment(s)
  • The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins.
  • Also acts on idarubicin.
  • It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro.
Cross-references
BRENDA2.4.1.327
EC2PDB2.4.1.327
ExplorEnz2.4.1.327
PRIAM enzyme-specific profiles2.4.1.327
KEGG Ligand Database for Enzyme Nomenclature2.4.1.327
IUBMB Enzyme Nomenclature2.4.1.327
IntEnz2.4.1.327
MEDLINEFind literature relating to 2.4.1.327
MetaCyc2.4.1.327
UniProtKB/Swiss-Prot
Q9L555, AKNK_STRGJ

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