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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.4.1.33

Accepted Name
Mannuronan synthase.
Alternative Name(s)
Alginate synthase.
Mannuronosyl transferase.
Reaction catalysed
GDP-alpha-D-mannuronate + ((1->4)-beta-D-mannuronosyl)(n) <=> GDP + ((1->4)-beta-D-mannuronosyl)(n+1)
Comment(s)
  • The enzyme catalyzes the polymerization of beta-D-mannuronate residues into a mannuronan polymer, an intermediate in the biosynthesis of alginate.
  • It is found in brown algae and in alginate-producing bacterial species from the Pseudomonas and Azotobacter genera.
Cross-references
BRENDA2.4.1.33
EC2PDB2.4.1.33
ExplorEnz2.4.1.33
PRIAM enzyme-specific profiles2.4.1.33
KEGG Ligand Database for Enzyme Nomenclature2.4.1.33
IUBMB Enzyme Nomenclature2.4.1.33
IntEnz2.4.1.33
MEDLINEFind literature relating to 2.4.1.33
MetaCyc2.4.1.33
UniProtKB/Swiss-Prot
Q9HY69, ALG44_PSEAE;  Q52463, ALG8_PSEAE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-