Home  |  Contact

ENZYME entry: EC 2.4.1.341

Accepted Name
Alpha-1,2-colitosyltransferase.
Reaction catalysed
GDP-beta-L-colitose + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine <=> GDP + alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine
Comment(s)
  • The enzyme, characterized from the bacterium Escherichia coli O55:H7, participates in the biosynthesis of an O-antigen.
  • The reaction involves anomeric inversion, and does not require any metal ions.
  • The enzyme is highly specific toward the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-beta-L-colitose.
Cross-references
BRENDA2.4.1.341
EC2PDB2.4.1.341
ExplorEnz2.4.1.341
PRIAM enzyme-specific profiles2.4.1.341
KEGG Ligand Database for Enzyme Nomenclature2.4.1.341
IUBMB Enzyme Nomenclature2.4.1.341
IntEnz2.4.1.341
MEDLINEFind literature relating to 2.4.1.341
MetaCyc2.4.1.341

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-