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ENZYME entry: EC 2.4.1.349

Accepted Name
Mannosyl-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis- undecaprenol 3-alpha-mannosyltransferase.
Reaction catalysed
2 GDP-alpha-D-mannose + alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comment(s)
  • The enzyme is involved in the biosynthesis of the linker region of the polymannose O-polysaccharide in the outer leaflet of the membrane of Escherichia coli serotypes O8, O9 and O9a.
  • It has no activity with N-acetyl-alpha-D-glucosaminyl-diphospho- ditrans,octacis-undecaprenol (Cf. EC 2.4.1.348).
Cross-references
BRENDA2.4.1.349
EC2PDB2.4.1.349
ExplorEnz2.4.1.349
PRIAM enzyme-specific profiles2.4.1.349
KEGG Ligand Database for Enzyme Nomenclature2.4.1.349
IUBMB Enzyme Nomenclature2.4.1.349
IntEnz2.4.1.349
MEDLINEFind literature relating to 2.4.1.349
MetaCyc2.4.1.349

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