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ENZYME entry: EC 2.4.1.363

Accepted Name
ginsenoside 20-O-glucosyltransferase.
Alternative Name(s)
UGT71A27.
Reaction catalysed
(20S)-protopanaxadiol + UDP-alpha-D-glucose <=> (20S)-ginsenoside C-K + H(+) + UDP
Comment(s)
  • The enzyme, characterized from the plant Panax ginseng, transfers a glucosyl moiety to the free C20(S)-OH group of dammarane derivative substrates, including protopanaxatriol, dammarenediol II, (20S)- ginsenoside Rh2, and (20S)-ginsenoside Rg3.
  • It does not act on the 20R epimer of protopanaxadiol, or on ginsenosides that are glucosylated at the C-6 position, such as ginsenoside Rh1 or ginsenoside Rg2.
Cross-references
BRENDA2.4.1.363
EC2PDB2.4.1.363
ExplorEnz2.4.1.363
PRIAM enzyme-specific profiles2.4.1.363
KEGG Ligand Database for Enzyme Nomenclature2.4.1.363
IUBMB Enzyme Nomenclature2.4.1.363
IntEnz2.4.1.363
MEDLINEFind literature relating to 2.4.1.363
MetaCyc2.4.1.363
Rhea expert-curated reactions2.4.1.363
UniProtKB/Swiss-Prot
A0A0A7HB61, U71A2_PANGI;  A0A0K0PVM5, UGT11_PANGI;  A0A068J840, UGT1_PANGI;  

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