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ENZYME entry: EC 2.4.1.40

Accepted Name
Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase.
Alternative Name(s)
A transferase.
Fucosylgalactose alpha-N-acetylgalactosaminyltransferase.
Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase.
Histo-blood group A acetylgalactosaminyltransferase.
Histo-blood group A transferase.
Reaction catalysed
UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1->2)-D-galactose <=> UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose
Comment(s)
  • Acts on blood group substance H.
  • Can use a number of 2-fucosyl-galactosides as acceptors.
Cross-references
BRENDA2.4.1.40
EC2PDB2.4.1.40
ExplorEnz2.4.1.40
PRIAM enzyme-specific profiles2.4.1.40
KEGG Ligand Database for Enzyme Nomenclature2.4.1.40
IUBMB Enzyme Nomenclature2.4.1.40
IntEnz2.4.1.40
MEDLINEFind literature relating to 2.4.1.40
MetaCyc2.4.1.40
Rhea expert-curated reactions2.4.1.40
UniProtKB/Swiss-Prot
Q9ET32, BGAT1_RAT;  Q8CFC4, BGAT2_RAT;  P16442, BGAT_HUMAN;  
P38649, BGAT_MOUSE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-