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ENZYME entry: EC 2.4.1.41

Accepted Name
Polypeptide N-acetylgalactosaminyltransferase.
Alternative Name(s)
Protein-UDP acetylgalactosaminyltransferase.
Reaction catalysed
  • UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine <=> UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
  • UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-threonine <=> UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine
Cofactor(s)
Ca(2+); Mn(2+).
Comment(s)
The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.
Cross-references
BRENDA2.4.1.41
EC2PDB2.4.1.41
ExplorEnz2.4.1.41
PRIAM enzyme-specific profiles2.4.1.41
KEGG Ligand Database for Enzyme Nomenclature2.4.1.41
IUBMB Enzyme Nomenclature2.4.1.41
IntEnz2.4.1.41
MEDLINEFind literature relating to 2.4.1.41
MetaCyc2.4.1.41
Rhea expert-curated reactions2.4.1.41
UniProtKB/Swiss-Prot
Q07537, GALT1_BOVIN;  Q6WV20, GALT1_DROME;  Q10472, GALT1_HUMAN;  
O08912, GALT1_MOUSE;  Q29121, GALT1_PIG;  Q10473, GALT1_RAT;  
Q6WV19, GALT2_DROME;  Q10471, GALT2_HUMAN;  Q6PB93, GALT2_MOUSE;  
P34678, GALT3_CAEEL;  Q9Y117, GALT3_DROME;  Q14435, GALT3_HUMAN;  
P70419, GALT3_MOUSE;  Q8I136, GALT4_CAEEL;  Q8IA42, GALT4_DROME;  
Q8N4A0, GALT4_HUMAN;  O08832, GALT4_MOUSE;  Q95ZJ1, GALT5_CAEEL;  
Q6WV17, GALT5_DROME;  Q7Z7M9, GALT5_HUMAN;  Q8C102, GALT5_MOUSE;  
O88422, GALT5_RAT;  Q5EA41, GALT6_BOVIN;  Q6WV16, GALT6_DROME;  
Q8NCL4, GALT6_HUMAN;  Q8C7U7, GALT6_MOUSE;  Q8MV48, GALT7_DROME;  
Q86SF2, GALT7_HUMAN;  Q80VA0, GALT7_MOUSE;  Q5RFJ6, GALT7_PONAB;  
Q9R0C5, GALT7_RAT;  Q9VUT6, GALT8_DROME;  Q9NY28, GALT8_HUMAN;  
Q8MRC9, GALT9_DROME;  Q9HCQ5, GALT9_HUMAN;  Q9GM01, GALT9_MACFA;  
A8Y236, GLT10_CAEBR;  O45947, GLT10_CAEEL;  Q8IA43, GLT10_DROME;  
Q86SR1, GLT10_HUMAN;  Q6P9S7, GLT10_MOUSE;  Q925R7, GLT10_RAT;  
Q7K755, GLT11_CAEEL;  Q8NCW6, GLT11_HUMAN;  Q921L8, GLT11_MOUSE;  
Q6P6V1, GLT11_RAT;  Q6DJR8, GLT11_XENTR;  Q8IXK2, GLT12_HUMAN;  
Q8BGT9, GLT12_MOUSE;  Q8MYY6, GLT13_DROME;  Q8IUC8, GLT13_HUMAN;  
Q8CF93, GLT13_MOUSE;  Q6UE39, GLT13_RAT;  Q96FL9, GLT14_HUMAN;  
Q8BVG5, GLT14_MOUSE;  Q8N3T1, GLT15_HUMAN;  Q9D2N8, GLT15_MOUSE;  
Q8N428, GLT16_HUMAN;  Q9JJ61, GLT16_MOUSE;  Q6IS24, GLT17_HUMAN;  
Q7TT15, GLT17_MOUSE;  Q6P9A2, GLT18_HUMAN;  Q8K1B9, GLT18_MOUSE;  
Q8MVS5, GLT35_DROME;  Q49A17, GLTL6_HUMAN;  

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